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P14124 (Cause: Cancer) is a whopping 4.5 Hour WU @ Start

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bcavnaugh
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2018/11/03 16:10:30 (permalink)
P14124 (Cause: Cancer) is a whopping 4.5 Hour WU on the GTX 1080 Ti @ 2037MHz and over 1,100,000 PPD @ 200,000 for Credit.
TPF: 00:02:40
 
Folding@home        Project Description      
Projects 14124-14131
Cause: cancer
These simulations are designed to test our understanding the folding mechanism of alpha-helical hairpins. We are trying to study how disulfide cross-linkers and sequence variants affect the folding thermodynamics and kinetics of these proteins, to learn how we might better use molecular simulation methods to design effective protein binder scaffolds, for use as "affibody" cancer therapeutics, for example.
List of Contributors
This project is managed by Prof. Vincent Voelz at Temple University.
 
Dr. Voelz's research focuses on using new simulation methods to unravel the mysteries of how proteins self-assemble into their functional folds, and to design folding and binding properties of proteins and peptide mimetics from first principles. The Voelz Lab participates in the Folding@home project, hosting two servers at Temple University. Dr. Voelz was formerly a postdoctoral scholar in the Vijay Pande lab at Stanford University.
post edited by bcavnaugh - 2018/11/04 11:17:28

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    bcavnaugh
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    Re: P14124 (Cause: Cancer) is a whopping 4.5 Hour WU @ Start 2018/11/03 20:32:31 (permalink)
    GTX 1080 Ti Pushing 2037MHz


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    #2
    scott@bjorn3d
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    Re: P14124 (Cause: Cancer) is a whopping 4.5 Hour WU @ Start 2018/11/04 03:22:31 (permalink)
    Have not seen one yet, I will keep an out for the RTX getting one.


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    STR1D3R_2
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    Re: P14124 (Cause: Cancer) is a whopping 4.5 Hour WU @ Start 2018/11/04 04:24:27 (permalink)
    bcavnaugh
    P14124 (Cause: Cancer) is a whopping 4.5 Hour WU on the GTX 1080 Ti @ 2037MHz and over 200,000,000 PPD @ 201745.4 for Credit.
    TPF: 00:02:40

    I have not seen one yet either. Curious how long it would take to complete on a 1060
    I think your finger may have stuttered on the ppd and added a couple extra zeros, if not wowsers


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    BadBertie
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    Re: P14124 (Cause: Cancer) is a whopping 4.5 Hour WU @ Start 2018/11/04 05:38:38 (permalink)
    P14134 yep just grabbed a couple of these on the Titan X pascals @ 1975mhz 4.5 hrs @ 2m 49s tpf 195,000 credit and just over 1mil ppd. I'll check what the final score is in a few hours.

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    BadBertie
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    Re: P14124 (Cause: Cancer) is a whopping 4.5 Hour WU @ Start 2018/11/04 10:40:55 (permalink)
    P14134 = only 195,696 final credit for me. Dropped my est. ppd by 400k with two gpus folding these. Maybe I got to squeeze the Titans (excuse me!) A bit more.

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    notfordman
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    Re: P14124 (Cause: Cancer) is a whopping 4.5 Hour WU @ Start 2018/11/04 10:50:35 (permalink)
    Did you notice what your TPF was by chance BB??
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    bcavnaugh
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    Re: P14124 (Cause: Cancer) is a whopping 4.5 Hour WU @ Start 2018/11/04 11:10:22 (permalink)
    scott@bjorn3d
    Have not seen one yet, I will keep an out for the RTX getting one.


    Never did get one on my RTX Card but both my GTX cards ran them overnight one is now.
    Going to try and get at lest one on my RTX card
    P11730 seems to be the only Project I am seeing on my RTX2,588,994.5 (23.351 WUs) PPD
     
    post edited by bcavnaugh - 2018/11/04 11:53:21

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    bcavnaugh
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    Re: P14124 (Cause: Cancer) is a whopping 4.5 Hour WU @ Start 2018/11/04 11:18:13 (permalink)
    STR1D3R_2
    bcavnaugh
    P14124 (Cause: Cancer) is a whopping 4.5 Hour WU on the GTX 1080 Ti @ 2037MHz and over 200,000,000 PPD @ 201745.4 for Credit.
    TPF: 00:02:40

    I have not seen one yet either. Curious how long it would take to complete on a 1060
    I think your finger may have stuttered on the ppd and added a couple extra zeros, if not wowsers


    Indeed a Typo Sorry
    P14124 (Cause: Cancer) is a whopping 4.5 Hour WU on the GTX 1080 Ti @ 2037MHz and over 1,100,000 PPD @ 200,000 for Credit.
    TPF: 00:02:40
     


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    #9
    BadBertie
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    Re: P14124 (Cause: Cancer) is a whopping 4.5 Hour WU @ Start 2018/11/04 11:48:11 (permalink)
    notfordman
    Did you notice what your TPF was by chance BB??


    yup 2m49s

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    #10
    bcavnaugh
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    Re: P14124 (Cause: Cancer) is a whopping 4.5 Hour WU @ Start 2018/11/11 13:04:09 (permalink)
    I did get one today on my EVGA GeForce RTX 2080 Ti XC ULTRA GAMING, 11G-P4-2383-KR Card
    TPF: 00:01:59 ETA: 3 Hours 15 Minutes PPD: 1683652.5 (7.261 WUs) and Credit: 231892
     

    Longer Run Time and Shorter Deadline
    post edited by bcavnaugh - 2018/11/11 13:10:54

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    BadBertie
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    Re: P14124 (Cause: Cancer) is a whopping 4.5 Hour WU @ Start 2018/11/12 04:56:41 (permalink)
    That's a bit more like it bcav. Might have to get me one of these newfangled 2080s

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    bcavnaugh
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    Re: P14124 (Cause: Cancer) is a whopping 4.5 Hour WU @ Start 2018/11/12 12:04:48 (permalink)
    BadBertie
    That's a bit more like it bcav. Might have to get me one of these newfangled 2080s

    If you do make sure it is a Ti Model.

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    scott@bjorn3d
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    Re: P14124 (Cause: Cancer) is a whopping 4.5 Hour WU @ Start 2018/11/14 09:07:22 (permalink)
    Man that's a great way to kill my points per day.  Things are killers.


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    bcavnaugh
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    Re: P14124 (Cause: Cancer) is a whopping 4.5 Hour WU @ Start 2018/11/14 09:13:07 (permalink)
    scott@bjorn3d
    Man that's a great way to kill my points per day.  Things are killers.

    Maybe bad for you but Good for Our Team

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    bcavnaugh
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    Re: P14124 (Cause: Cancer) is a whopping 4.5 Hour WU @ Start 2018/12/02 14:11:13 (permalink)
    Only got one WU Today, was hoping to see a second one on the RTX Cards to see what the Driver Difference is.
     
    post edited by bcavnaugh - 2018/12/02 14:57:30

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    Cool GTX
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    Re: P14124 (Cause: Cancer) is a whopping 4.5 Hour WU @ Start 2018/12/02 21:25:30 (permalink)
    3 Hr 18 min to Run this WU on a RTX 2080Ti  (GPU @ 2055 & 61C  on Air)
     
     
    Project 14124 (9,1,86)
    TPF 2 min

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    Teknogroovie
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    Re: P14124 (Cause: Cancer) is a whopping 4.5 Hour WU @ Start 2018/12/03 06:57:08 (permalink)
    Both my 1050 ti and 1050 have this project running right now.  13 hours for the 1050 ti PPD at 7504 and 14 1/2 hours for the 1050 PPD at 5928.   I feel like Stanford it trying to help EP win.  LOL  It's for a good cause so that's all the really matters. 

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    bcavnaugh
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    Re: P14124 (Cause: Cancer) is a whopping 4.5 Hour WU @ Start 2018/12/03 15:34:00 (permalink)
    2080 Ti TPF: 00:02:00 | 1464167.7 (7.2 WUs) | @ 53% 01:34:00 Time Left | Credit 203356.6

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    Cool GTX
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    Re: P14124 (Cause: Cancer) is a whopping 4.5 Hour WU @ Start 2018/12/03 15:45:43 (permalink)
    I've seen these on RTX & 1080 Ti (4+ hrs...)  killing my PPD
     
    I do not have an account on Stanford Folding @home so I can't send this up for anyone's attention - to possibly consider
     
    These are killer WU & either they should earn many more points or be reduced in size
     
    My 2080Ti will PPD at 2,250,000 almost any WU some more, some less ....
     
    these 14124 gave an estimate 1.6 Million PPD... (a 28% drop in PPD for those cards) - obviously their points system is less than perfect

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    bcavnaugh
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    Re: P14124 (Cause: Cancer) is a whopping 4.5 Hour WU @ Start 2018/12/03 15:48:07 (permalink)
    I will look now.
    Project 14124(GPU, OpenMM21) to BETA
    Project 14124(GPU, OpenMM21) to ADVANCED
    OpenMM21 project 14124 to FAH
    Project 14124 what wrong with you?
     
    No Change, no real useful information.
    post edited by bcavnaugh - 2018/12/03 15:59:30

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    Re: P14124 (Cause: Cancer) is a whopping 4.5 Hour WU @ Start 2018/12/03 16:16:51 (permalink)
    number of atoms: 13839
     
    stats credit: 38000  
     

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    bcavnaugh
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    Re: P14124 (Cause: Cancer) is a whopping 4.5 Hour WU @ Start 2018/12/03 16:23:35 (permalink)
    There are More Projects 14124-14131

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    #23
    bill1024
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    Re: P14124 (Cause: Cancer) is a whopping 4.5 Hour WU @ Start 2018/12/03 21:12:50 (permalink)
    Keep in mind this PPD decrease happens to everyone, so there is no real disadvantage. 
    These folding WUs aren't that long, I am finishing up a 6 day 14 hour GIMPS prime95 task now.
    The other GIMPS task with a GPU folding will be 15 days. On an i7-8086k at 4.4
    Folding is hurting GIMPS, but the GTX1080 is doing over 800k PPD
    GIMPS is using all 6 cores. i5-8600k at 4.4

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    ipkha
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    Re: P14124 (Cause: Cancer) is a whopping 4.5 Hour WU @ Start 2018/12/04 08:07:07 (permalink)
    Thus the dangers of beta and advanced flags. I'm not seeing any of these and I think advanced is set for my rigs.


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    bcavnaugh
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    Re: P14124 (Cause: Cancer) is a whopping 4.5 Hour WU @ Start 2018/12/04 10:14:07 (permalink)
    ipkha
    Thus the dangers of beta and advanced flags. I'm not seeing any of these and I think advanced is set for my rigs.

    I use the Advanced Flag but when this Project was under Beta 5 Weeks ago I stated to get them.
    But now this Project is not Under Beta or Under Advanced Flags
     
    OpenMM21 project 14124 to FAHby vvoelz
    » 13 Nov 2018, 13:18
    We are releasing OpenMM21 project 14124 to FAH (was on ADVANCED)

    These simulations are designed to test our understanding the folding mechanism of alpha-helical hairpins. We are trying to study how disulfide cross-linkers and sequence variants affect the folding thermodynamics and kinetics of these proteins, to learn how we might better use molecular simulation methods to design effective protein binder scaffolds, for use as "affibody" cancer therapeutics, for example.
     
    project number: 14124
    stats credit: 38000
    timeout: 5
    deadline 7
    k-factor v=0.75
    number of atoms: 13839
     
    The Trail
    Project 14124(GPU, OpenMM21) to BETA 18 Oct 2018
    Project 14124(GPU, OpenMM21) to ADVANCED 01 Nov 2018
    OpenMM21 project 14124 to FAH 13 Nov 2018
    post edited by bcavnaugh - 2018/12/04 10:30:56

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    #26
    ipkha
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    Re: P14124 (Cause: Cancer) is a whopping 4.5 Hour WU @ Start 2018/12/04 10:31:42 (permalink)
    Were the credits the same in beta and advanced? Maybe the units flagged as beta and advance are using old point calculations.


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    bcavnaugh
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    Re: P14124 (Cause: Cancer) is a whopping 4.5 Hour WU @ Start 2018/12/04 10:43:11 (permalink)
    ipkha
    Were the credits the same in beta and advanced? Maybe the units flagged as beta and advance are using old point calculations.

    Did not go that far into it. But I do remember seeing HFM.NET get a few updates on this Project.
    As long as I do not get this Project I can stay above 16,000,000 PPD but will Drop below if I do get one.
    post edited by bcavnaugh - 2018/12/04 10:44:42

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    SM-71
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    Re: P14124 (Cause: Cancer) is a whopping 4.5 Hour WU @ Start 2018/12/16 17:13:09 (permalink)
    I got and finished one of these today, seems to be a good work unit for my GTX 970 5min 36sec per frame avg for 9.33 hours to complete - Last 10 completed WU's as recorded in HFM:
     

     
    Actual credit was 139004 btw...  I would be fine running them back to back to back so that you guys with the faster GPU's don't have to do these slow work units  
     

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    bcavnaugh
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    Re: P14124 (Cause: Cancer) is a whopping 4.5 Hour WU @ Start 2018/12/16 17:15:38 (permalink)
    SM-71
    I got and finished one of these today, seems to be a good work unit for my GTX 970 5min 36sec per frame avg for 9.33 hours to complete - Last 10 completed WU's as recorded in HFM:
     

     
    Actual credit was 139004 btw...  I would be fine running them back to back to back so that you guys with the faster GPU's don't have to do these slow work units  
     

    Wow! Almost 10 Hours.

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