bcavnaugh
" I can hear it sitting 3 feet away when the room is silent." With the side cover on or off?
Did you Bleed the air into the Radiator before you installed it, by rotating the Pump and Radiator before you installed.
And keep the GPU Lower than the Radiator and with the Radiator Tubes on the Bottom as how you now have it installed.
 
 
 
I do no see any Cool Air Intake or (Fresh Air Flow) for your GPU to use?
It looks like you only have Hot Air coming into your Case from the Front CPU Radiator.
What are your Temperatures on your GPU? 

bcavnaugh
This is true about a Break-In Time Frame.
I have been using the Hybrid Coolers since it came out for the GTX 980 Cards and one GTX 1070 Hybrid.
I have been using Corsair AIO Coolers for a few years and have to Bleed the Air in them as well.
Now I have my First EVGA AIO CPU Cooler to play with.

bcavnaugh
My Hybrid has never seen 60 Degrees, maybe 46C
You can remove it and try to but it would not hurt.
I use an old PSU to power the Pump when I do mine.
You will really here the Pump when you air passes through it so you will no when their is none. It is Loud.
 
You can reverse your Fan on the GPU Radiator and make it an Intake and it will pull in cooler air and out the Top of your CPU.
Not seeing the rear of your computer case but are you running another fan on the outside in a Push/Pull setup?

bcavnaugh
I would set the Memory to Zero and Move the Voltage to the Max using your current +250.

 

bcavnaugh
My Blower Fan run at 60% using XOC.
This Blower Fan is what cools the PCB and vRam and Chokes and all.
 
Yours I thinks I running so hard because you have no fresh air coming into you case, only hot air from your front fans coming of the CPU AIO Radiator.
And you are overclocking your vRam.
I do not use "HWMonitor" use XOC to see what the Blower Fan is running. I think the Max is under 10,000 RPMs.

X-TAC
Unfortunately, the buzz appears to be normal and there are several other threads on the front page complaining of the same thing.  I have been through two already, both with the identical high RPM pump whir.  Air bubbles tend to create an uneven or variable pitch.  If yours is like mine, it's just a constant steady hum, like sitting in an industrial plant full of fluorescent lighting and machinery.  I am disappointed and the unique design of the center "extended" cold plate is what makes this work.  Since Asetek likes to make the cold plates very difficult to remove, trying to swap in another AIO cooler with a better pump would be difficult.
 
Your GPU should idle around room temperature, or more specifically your case ambient temperature.  29C is high, but not if it's Summer and your room temps are in the mid to upper 20's.  You may need to take a look some other case temps.  The front waste heat coming in should not dramatically affect the GPU water temps since the radiator is in back.  However, if you are dragging all the exhaust from the case through it, that would lead to higher coolant temps as well.  Regardless, if you are starting at 29C idle, all your GPU temps will be 10C higher than mine since I am starting at 19C in a cool room.  That would seem to be the difference, rather than a contact/TIM kind of problem.  Hopefully, that is an SP120 on the radiator in back.  An AF120 would not be particularly effective on its own and might lead to higher coolant temps as well.