Setup:
-GPU: EVGA GeForce RTX 3080 FTW3 ULTRA GAMING, 10G-P5-3897-KL, BIOS ver. 94.02.71.40.AA, Driver ver. WHQL Game Ready 471.41
-CPU: AMD Ryzen 5 5600x
-Cooler: Noctua NH-D15S
-Motherboard: Asus TUF GAMING X570-PRO (WI-FI), BIOS Ver. 4002
-Memory: Corsair Vengeance RGB Pro 32GB (4x8GB) DDR4 3200 PC4 25600 CMW32GX4M4C3200C14
-Storage: 1TB Samsung 970 Pro, 4TB Samsung 860 Evo, 2TB Seagate Barracuda 7200RPM 256MB Cache ST2000DM008
-Power Supply: EVGA SuperNOVA 750 G3
-Case: Fractal Design Meshify 2 Compact
-Monitor: Acer Predator X34 GS
-Operating System: Windows 10 21H1
 
Issue:
Recently purchased an EVGA GeForce RTX 3080 FTW3 ULTRA GAMING on 07/12/2021 and upgraded from a Gigabyte GeForce RTX 3060 Ti GAMING OC PRO 8G (rev. 1.0). The RTX 3060 Ti has been working in my system flawlessly since March of 2021 with no issues. While gaming (usually during longer 2.5-3hr sessions), monitor will suddenly lose input signal and result in a black screen. I can still hear the game in the background and can hear the actions I am performing in game as they are happening. This has occurred twice since installing the card on 07/15/2021. Both times were while playing Prey (2017). FPS in game is capped to 144fps and power draw is being reported as high as 520W from my APC battery backup UPS. GPU temps peak at 84C and CPU temps peak at 70C. After the first occurrence, I performed a reboot and my BIOS prompted me to either continue with current settings press F1 or enter the BIOS and enable CSM as the UEFI drivers are not supported for my video card. I pressed F2 and before I could switch menus my screen went black again. To remedy the black screen, I had to pull the GPU, reset CMOS, and re-install the GPU. I left CSM disabled, UEFI set to Windows OS, and kept Resizable BAR enabled. After the second occurrence, I performed a reboot and still had a black screen. This time I reset CMOS, but the black screen persisted. So I reset CMOS (removed battery), pulled the GPU, and reinstalled both. I was able to get back into the BIOS and have since enabled CSM and disabled Resizable BAR. Once I was able to boot, I rebooted into Safe Mode, ran DDU and wiped all drivers, settings, and cache. I rebooted back into Windows 10 and re-installed WHQL 471.41. Both occurrences resulted in an error logged in event viewer which was Error 4101, Display driver nvlddmkm stopped responding and has successfully recovered.
 
As I am not 100% sure what the issue is, I am led to believe that this may be a PSU related issue. I know that the EVGA SuperNOVA 750 G3 is at the bare minimum recommended PSU requirement in terms of wattage. I do not have another PSU to test, unfortunately, and also no other computer that I can test the RTX 3080 with. I'd like to see if any others have any input related to this issue as I'd like to see if I can narrow it down further before spending money on a new PSU.
 

DisplayPort and I have tried different cables and different monitors. At this point I've reseated the GPU twice since the initial install, since the issue requires me to remove and reinstall the GPU for it to display anything again.

Sajin
Time to see if the issue follows the card to a known good working system.

Yeah, that's a problem for me. No other system and no friends that have a capable system, unfortunately. That was my initial thought though, but I might just have to suck it up and buy a PSU to be able to rule it out. Hopefully, a new PSU fixes it.