That is why they are called Server Motherboards, myself I am looking at the 7048A-T with the X10DAiMB.

FYI
Ordered on July 30, 2013 Asus KGPE-D16 AMD Opteron Server Bd
This ASUS Server Motherboard lasted only 8 Months and 3 Months in their RMA Process. ASUS NEVER AGAIN 
When I got it back I gave it away as a Giveaway and bough this Server Motherboard Super Micro MBD-H8DGi-F
 
In the last few days I have ordered this Server:
210-ACWJ 1 PowerEdge T630 Server
338-BJDO 1 Intel Xeon E5-2680 v4 2.4GHz,35M Cache,9.60GT/s QPI,Turbo,HT,14C/28T (120W) Max Mem 2400MHz
338-BJEE 1 Intel Xeon E5-2680 v4 2.4GHz,35M Cache,9.60GT/s QPI,Turbo,HT,14C/28T (120W) Max Mem 2400MHz
370-ACPH 1 2400MT/s RDIMMs
370-ACNS 1 32GB RDIMM, 2400MT/s, Dual Rank, x4 Data Width
370-ACNS 1 32GB RDIMM, 2400MT/s, Dual Rank, x4 Data Width
405-AADS 1 PERC H330 RAID Controller
400-AIFU 1 200GB Solid State Drive SATA Mix Use MLC 6Gbps 2.5in Hot-plug Drive,3.5in HYB CARR, S3610
400-AIFU 1 200GB Solid State Drive SATA Mix Use MLC 6Gbps 2.5in Hot-plug Drive,3.5in HYB CARR, S3610
429-AAHW 1 DVD+/-RW, SATA, Internal
618-BBDS 1 Windows Server 2012R2 Standard Edition,Factory Installed, No Media, 2 Socket, 2 VMs,NO CALs
489-BBBV 1 T630 GPU Installation Kit
412-AADX 1 160W Heatsink for PowerEdge T630
412-AADX 1 160W Heatsink for PowerEdge T630
325-BBHK 1 Bezel
450-ADWM 1 Dual, Hot-plug, Redundant Power Supply (1+1), 1100W
750-AAFF 1 Redundant Fan, Dell PowerEdge T630
 
I did almost get this one 7048A-T with the X10DAi though.
 

This kind of thing is down to luck, and the luck has been getting worse in recent years as margins get squeezed, QA gets reduced and not enough spares get made to service replacements during the warranty period. I have two SR-2s. One I bought 2nd hand on ebay and that one always worked (within the envelope of the SR-2's many design faults). The other I bought new, and it was replaced 3 times within the first year (by refurbs, since there were no new spares left within a year of it going out of production, despite 7 years of warranty remaining).
 
Granted, EVGA's customer service is superb, and Asus' is known to be by far the worst in the entire industry, but from personal experience, the engineering situation is inverted. As you can see from my sig I have replaced my SR-2 with a Supermicro X8DTH, and I am much, much happier with it.
 
Also, if you have been having problems with two different motherboards from two different manufacturers, it may be a good time to invest into a new high end PSU (top of the line EVGA, CoolerMaster or Corsair, read reviews on amazon to narrow down your choice). A good earthing wrist strap might be worth investing in, too.

<p>Im in the process of getting a Z10PE-D8 WS from RMA again, second time,</p> <p>The Supermicro that i currently have, might have to send back to warranty as well, it also has some problems !</p>
 
THe Z10PE-D8 WS was perfect for what i intended, then it had become problems, and i was fed up with it, and didnt wanted to go through the rma again. So i bought the supermicro.
From the PCI Express ports the ASUS is better. From the RAM ports and LAN, the Supermicro is better, the problem with supermicro is that im not sure SLI works. I had problems booting with two 295x2, reason why i sold them back (was so sad about it)
Two 295x2, are the reason i have two antech 1300 PSUs, they are more than enough for stable power delivering. Wanted to get a TItanium 1600 EVGA at the time, but was not on the market at that time.
 
Will test two Arctic storm 1080 in Asus returned from RMA.
Wisch there was a real good EVGA mainboard for dual xeons on the market though !
 
WHat i would consider would be the 11 PCI Express port motherboard from Supermicro.