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Yes, it is very rare to have to take apart a card.
I think the last one I had to do (for dust/buildup) was an nvidia 4400 ?
That blower sucked up everything, and I had a dog that could go anywhere and I got massive hair buildup that could not be blown backwards out of the card. I had to take the blower apart to remove the hair buildup.
But, that was a dog plus a very damp place plus lots of dust.
Very rare indeed.

use anti static makeup brushes to get at the hard to reach areas.

Dr.Death
ya, true a reference blower card you may need to remove the shroud to get good in there   if extreme  dust built up   . I find it best to blow out my rigs like on a 2 month maintainece  or as it loks to start to need a quick inspect and clean .  don't let it get too bad  and that makes it a tad bit more easy to keep up and clean  [opinion] dust could build up and hold static  as well  [more opinion ] 

Yep, this is when I started cleaning every month or 2, and have never had an issue since (involving dust or dirt or hair, anyway).
I actually bought a little handheld shopvac just to suck up the dust out of crevices, like what accumulates in the fins of AIO coolers. It isnt very powerful, but just enough to get the dust out without hurting any fans or anything.
Something like this cheapy (although I think mine is 1/2 that horsepower, doesnt do wet, and came with nowhere near the accessories that does, lol):
https://www.walmart.com/i...P-Wet-Dry-Vac/15406606