I think this topic has been beaten to death many times over, and the OP has had his issue explained. Let's move on. :)

Well, I prefer to set sampling rate same as audio source. Nu Audio has two clocks - one for 44.1 and one for 48 khz. Set base sampling rate as an integer multiplier of the source sampling rate. Don't make the system convert 44.1 to 48 and vice versa.
 
As for the bit rate, I may be wrong but keeping it high is always good as it minimizes the reduction in dynamic range by low volumes set in system mixer. 
 
Actually, high sampling rates are fine when you run DSD (but why?). Also they are really great for studio usage since you can record the data with best possible quality for all your downmixing needs. Its as simple as flac - a difference or no, use the best because you can.

Vivicector

socialwaif
I am still trying to figure out what "standard CD/DVD quality bitrates" are. Are they 24-bit depth at 48 kHz sample frequency?

CD standard is 16bit/44.1 khz. DVD used 48khz. Modern hi-rez audio runs 24bit/44.1 or 24bit/48. Vynil copies are done in different modes depending on the releaser. 192 khz/24 bit is what I see a lot (lets leave all the vynil analog business out of this topic)

Thanks. I am currently trying out the 24bit/48 setting in a few games.

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