I've used them before. They work fine. Now I use a 4 way connecter with one of these attached:
 
http://www.frozencpu.com/products/14594/ex-tub-1033/Bitspower_G14_Mini_Valve_-_Silver_BP-MVV-SLBK.html
 
Makes it easy to drain for, me, less mess. Just turn the valve.

No, but I am using a I use a 4 way connecter and a  Koolance quick release. 

Same Drain but with QD, bottom Right on lower Radiator.
I have a Black Cap on the QD, it comes with it. 
 Click on Image for a Larger View.

QD's are crazy expensive.  Think I ended up spending $300 or something on them for my loop.  You can get away with T fittings and a plug in one end if you want to do it cheap.  You can see one of those in my mod rig link...I didn't really need to do it but I was going to be running an elbow anyways so not much more effort to put a T in there for draining.

 
What is your Flow Direction? The Drain would need to be at the lowest point and best on the return line.

 
That may not be the best case for a Custom Water Loop.
What does the inside look like?

I'm starting to think water for this case is too crazy?
 



 
Yeah, just too tight? To use use this case, opinions? AIO for the cpu and aio-gpu, on a single GPU?

AnonymousGuy
QD's are crazy expensive.  Think I ended up spending $300 or something on them for my loop.  You can get away with T fittings and a plug in one end if you want to do it cheap.  You can see one of those in my mod rig link...I didn't really need to do it but I was going to be running an elbow anyways so not much more effort to put a T in there for draining.

I agree however I doubt I will have to buy any more in the future assuming I only have one water cooled system at a time. I put a few sets in for making it easy to remove the top of my case (Mountain Mods Extended Ascension) and as I was at it I put a few extra in isolating my GPU stack (4-way SLI). Due to this I can pretty much work on sections of my loop without having to drain the entire thing.
 
I forgot to mention, I have air-exhaust plugs on my fill ports as well as a spot to break a vacuum on a spot in a loop and on one of the ports on the top GPU of the GPU stack. I can just press the button when I am draining via the quick disconnect to start and stop the drain as well as if I disconnect the top and bottom of my GPUs I just hook up my drain connection to the bottom connect and press the button to vent the cards to drain. It is great to really control how much and how fast to drain the loop.  Isolating the cards also helps if I have to pull out one for testing. I can pull all of my GPUs in about 15 minutes without having to drain the whole loop.
 
I also have a few valves on either side of a filter (Innovatek Particulate filter 501531) to isolate it for cleaning the filter and I can use that as well to minimize flow when working on a part of the loop, just make sure you open the valves again before turning the system back on . I put a silver bullet kill plug into the loop next in the areas that can be isolated to allow it to be changed without having to drain the loop to change as well.

You could also get or make one that sits on top of your case.
The Key here is the copper/brass radiator stay away from aluminum radiators.
 
 
http://koolance.com/index.php?route=product/category&path=54_85

  $81.99 3x120mm Radiator Enclosure/Riser 
Or you could rig One or Two of this item on top of your case
 $44.99  Radiator Mounting Bracket with Quick-Release   SKU: BKT-HX001

 $34.99  3x120mm Fan Radiator Shroud, Black   SKU: SHR-1020BK
 
$24.99  Radiator Shroud Mounting Bracket, Black Plate   SKU: BKT-HX003BK *Not needed if SKU: BKT-HX001 is used.
 

I would go with this one but I think it may look funny, but you can come up with nice sides.


 $84.99 Radiator, 3x120mm Fans, 54mm Thick, 30-FPI Copper   SKU: HX-360XC
This one fits inside the Enclosure/Riser.
$59.99  Radiator, 3x120mm 30-FPI Copper   SKU: HX-CU1020V
 $2.99 Radiator Mounting Screw & Nut, 38mm   SKU: BLT-HX038 3 Each
 $10.24 Fan, 120x38mm, 116CFM 6 Each for Push/Pull 3 Each for Push or Pull.
 $2.49 Fan Grill, 120mm 3 Each A MUST for the 120x38mm, 116CFM Fans
 
$9.74 Fan, 120x25mm, 108CFM 6 Each for Push/Pull 3 Each for Push or Pull.
 $2.99 Radiator Mounting Screw & Nut, 25mm   SKU: BLT-HX025 3 Each
 $74.99 CPU-380I Water Block (Intel Processor)   SKU: CPU-380I
$76.99 PMP-500 Pump, G 1/4 BSP   SKU: PMP-500
 

$17.99 Reservoir Fitting Base (60mm OD)   SKU: COV-TKBTM
 $11.99 Reservoir Body, 60x80mm (WxL), 157ml   SKU: BDY-TK080
or even
$7.49 Reservoir Body, 60x50mm (WxL), 98ml   SKU: BDY-TK050
 $9.99 Reservoir Top with Fill Port (60mm OD)   SKU: COV-TKTOP
$5.95 Reservoir Bracket, 140mm (60mm OD)   SKU: BKT-TK140F
 
 $169.99 CTR-CD1224 12V or 24V Pump & Fan Controller With Display   SKU: CTR-CD1224
 $19.99 INS-FM17N Coolant Flow Meter   SKU: INS-FM17N
$5.49  4-Fan Wiring Harness, 3-Pin   SKU: CBL-NX006P Get 2 Each

 
$17.99 Coolant Temperature Sensor, Brass, 10K Ohm   SKU: SEN-AP008B One Or Two
$9.99 Coolant Temperature Sensor Plug, 10K Ohm   SKU: SEN-AP008G Extra
$4.49 Temperature Sensor, Flat, 10K Ohm   SKU: SEN-AP007P * You get some with the CPU-380I I put one on the bottom of the CPU Water Block one on the CPU Back Plate. You have one more that you would use for the Water using the SEN-AP008B above. This covers the three Temperature Sensor on the CTR-CD1224.
 
 $2.19 Tubing, 1ft (305mm) Clear UV-Reactive PVC, 13mm x 19mm (1/2in x 3/4in)   SKU: HOS-13X19CL
Hose Clamp for OD 19mm (3/4in) $1.39
 
$11.99 QD3 Male Quick Disconnect No-Spill Coupling, Male Threaded G 1/4 BSPP *Black*   SKU: QD3-MSG4-BK 3 Each for the Radiator + 1 for your Drain System One of Each
 $15.24 QD3 Female Quick Disconnect No-Spill Coupling, Compression for 13mm x 19mm (1/2in x 3/4in) *Black*   SKU: QD3-FS13X19-BK 3 Each
 $10.99 Computer L-Bracket with G 1/4 BSPP Threads Sorry no Black
 $12.24 Fitting Single, *Black* Swiveling 90-Degree, G 1/4 BSPP   SKU: ADT-DXG90-BK 4 Each


$6.74  Fitting Single, Compression for 13mm x 19mm (1/2in x 3/4in) *Black*, G 1/4 BSPP   SKU: FIT-V13X19-BK 6 Each

 $14.99 Koolance LIQ-702 Liquid Coolant Bottle, High-Performance, 700mL (UV Blue)   SKU: LIQ-702BU-B
I use it and have no problems, I also use (UV Red)
 
Also Do Not use a Silver Kill Strip or Coil in this system.
BECAUSE:

Liquid Coolants

Koolance's product warranty does not cover the use of 3rd-party coolants, coolant additives, or corrosion. Koolance LIQ-702 or LIQ-705 coolants are strongly recommended to help avoid issues with mixed metals or biological growth. Additionally, do not use aluminum with bare (unplated) copper or bare (unplated) brass in the same system. Do not use silver with nickel in the same system. 
 
All Counts are Estimates only.

Probably just do air and low watts for this case, I just wanted a sleeper look with this case.  Just do my water build for a custom case.
 
This case, just too damn tight...