EVGATech_BrandonS
Some programs make use of the C++ redistributable, so it's always a gamble when uninstalling older version. It shouldn't cause any permanent damage to uninstall them, but you'll probably get errors until the correct version is re-installed. Personally, I'd recommend re-installing Windows if you haven't done so since 2012. 

Cool GTX
No, it's hard to tell what installed which version and it is Not backwards compatible
 
C++ does not get updated usually at an individual program level unless the publisher releases an update.  So, older versions Are Needed for the program that installed that version.
 
Move them to a safe location and see what happens.  If your program does not work move it back