I'd agree with this as well, and add a couple more details:
If you run it without the middle fan (which isn't causing an issue) then it still happens on the 3rd fan, so if there's any concern over power delivery or a problem with the entire chain, then I think that can be ruled out (I'm not an expert, but my basic knowledge of circuitry should be sufficient here so please correct me if I'm wrong)
The sound is absolutely gone when the 3rd fan is disabled in X1, and I don't think it's a fan issue whatsoever. A friend of mine got the same exact card, and he plugged the beige (2nd) fan into the blue port, and the blue (3rd problematic fan) into the beige port. He reported that it was then the middle fan acting up. This makes me think it's the PWM controller as everyone is saying and is either a hardware issue, or something that can hopefully be fixed with a firmware update which would save EVGA a heck ton of money in shipping/RMAs.
For now, I've disabled the problematic fan and am only going to use it in light workloads until my ticket gets an answer. It's the weekend so I imagine they're going to get back to me monday once they see how this thread has blown up.
Best of luck to all of you who waited in line/got lucky and are now suffering this noise!