I'm using all Bitspower fittings which are not in any way blocking the flow. Taking the tube off the top of the inlet on the reservoir, I can suck some water through both water blocks and radiator. I just can't seem to get the pump to prime even giggling and tilting the system around. The only thing I can think of is that the pumps are air locking on me, as Kougar said. But both D5 and DDC having the same issue really confuses me.

Thanks anyways for the help. Seems this Forum is good. I look forward being here.

KKnoll
Thanks anyways for the help. Seems this Forum is good. I look forward being here.

 
 
We try to Help
 
OK, couple more ideas, though have issues with Both types of your pumps -- seems to indicate the blockage is somewhere in your loop
 
Mfg defect of the pump body - blocked ? 
 
The O-ring on D5 pump can "set" the gap between rotor & pump housing - maybe its touching ?
 
So, if you blow into one of those (extra) inlet ports on your D5 combo what happens -"pressurize the reservoir"

Protium 150 D5/Reservoir Combo Acetal (Stand Alone)       8 ports, 1 outlet, 7 inlets
 
It is almost Always the little things that cause all the trouble - some small detail

Are you sure the power plugs wiring on the pump is the same as the plug coming from the psu/mobo etc... ? Maybe that the wiring is different for different manufacturers. Sure sounds like impeller not turning. 

Looks like Cool GTX has your back! Some extra questions for clarification, is this D5 new or was it in use before your rebuild?? Just so I understand clearly, was it stock or did you mount a block to the D5?
 
The D5's can be opened up and you can inspect the impeller and check for debris that way. The vibration is a good sign. If this was a well-used D5 then gunk from the past loop may have gotten in there and is simply blocking water flow or preventing the impeller from turning at speed. All those additive fluids break down eventually and can cause issues. This vid shows the D5 impeller, could be gunk inside like there was with his https://www.youtube.com/watch?v=vRGS4GJ-NQU

Sorry I've been away. I've been extremely busy with other things in life. I'm glad to see I'm getting a lot of support with my problem. Great community here on the EVGA Forums.

Wmmills, either pump is working. I can guarantee this.

Kougar, Pumps and blocks are cleaned. I've taken apart everything and inspected, cleaned and put together again. I like how you sent the link to Jay's Two Cents. I'm a follower of his channel.

Cool GTX, pumps are running as they should. I get a little bit of a cyclone effect but not enough to cause air into the pump. It is worse with the 150 mm reservoir. I've even tried my 250 mm reservoir on both pumps for more gravity feed pressure.

Blowing into the one of the spare ports at the top of the reservoir doesn't do much for pressurizing the reservoir. I'm a smoker for 20 plus years. Lungs aren't up to it any longer. Haha.

I've tried to disconnect the last hose running from the GPU block to the rad this morning and trying bleed out air while the pump was running. No luck. It's like I don't have enough 'Head Pressure' with either pump.

To all, I'm going to leave the pump on by its self all day today with the reservoir open for air to escape to see if it will prime enough to get the flow going. So far, the past hour it's filled everything, CPU, GPU and radiator but there seems to be air still in the line between pump and CPU block, CPU block and GPU block and between the GPU block and rad.

Thanks again for all the help. Again, I really appreciate the community here.

Silly question, but I have to ask... is this a PWM or set speed pump? (3 wires versus 4)

If it is a set speed, make sure it is turned up to 11 (actually 5, since that is max).

If it is PWM, make sure it is reading proper speeds and is turned up at the fan header, and that the fan header is set to PWM.

If everything is at max, you may need to check each part individually as something has a blockage somewhere. Taking everything apart will be tedious, but you will need to check all of the passes or at least make sure air will make it through relatively unrestricted.

It could be something simple like a dislodged jet plate on the cpu block or GPU block causing the issue.

Thanks The Scarlet one. I actually just finished putting it all back together after checking everything over. Turns out I put the cold plate on the CPU block on wrong. 🤦‍♂️Turned it 90 degrees and I know have flow. Thanks everyone for all your help. Problem is now solved and the CPU is running between 60 - 65 and GPU at 42 on full stress test. Going to be good to game again.

Awesome! It is very very easy to turn one of the parts, especially with the CPU, just a little off center and block the flow. Very glad you found the culprit and very glad you are back up and running :-)

Hah, pretty funny. Glad ya found the problem!