Disable Hardware Acceleration in Chrome
Is Winamp FLAC and MP3 Current?
Make sure you have the Current Chipset Drivers installed
I updated chipset drivers and disabled hardware acceleration in Chrome.
Still getting audio skipping from Chrome audio playback.
Edit: Possible solution, I manually updated in Device Manager each of the ASMedia Extensible Host Controller (3.0, 3.0 and 3.1) entries in Device Manager using the "Search automatically for updated device driver software" option. The version installed from EVGA was dated Sep 2018, and the Microsoft-found auto-updated version is 22.214.171.124, dated Aug 2016 instead, but the Microsoft version is working now. Going on an hour of testing and zero skips/dropout so far.
TLDR: The EVGA driver package 0.1.1 may have a buggy driver for the USB controller on the Nu Audio card. Try manually updating the three "ASMedia USB3.x Extensible Host Controller" items with whatever Microsoft finds as an auto-update driver and your problem may be fixed, mine appears to be.