Just to put my experience down. I've been dealing with this issue for months. Got my 2nd card via RMA a month ago. Same thing, tried everything I could to try and isolate the issue. Thought, it can't be the GPU at this point. Last night, after receiving new parts, I built an entirely new computer, besides the 3080. Nothing is common with old PC. Less than 2 hours run time exact same issue. It seems to get worse and worse as well the more it happens. Same nvlddmkd Error viewed in Event Viewer.
 
Talked with EVGA customer support, we're trying a third card. At this point I don't have a functioning PC. EVGA can't offer anything beyond a sorry a try a new card. I asked if they're working with Nvidia to get this pinned down. To me it just has to be a driver issue. The guy didn't really know. Unless I've (we've) been extremely unlucky with bad cards, this issue doesn't seem to have a resolution in sight.
 
I will say its nice to see a good community, not only on EVGA's site. I've tried everything people have suggested across many forums. People are definitely putting in the time to try and fix this, not just relying on customer support. Think what we all want is just some sort of high level recognition from Nvidia/EVGA, that yes this is a driver or something else issue and they're working to resolve it. 
 
At this time, I've basically given up with the 3080. I'm hoping after resetting everything, the 1080TI I have will work again. Before when I tried putting it back in (older PC) it was having issues. But that could just be residual effects from driver getting messed up from 3080 or something. 
 
I'll update if the third card works, but I don't have a hope with that. Thanks for all the suggestions here, cheers to everyone, and hope your screens stay bright!

have you found a solution i have the same issue?

So I followed benattar's advice and disabled lighting service + deleting the folder.
 
"https://forums.evga.com/RTX-30803090-Black-screen-possible-solution-m3137072-p9.aspx"
 
So far no black screens (4 hours). will update

I will try that next I did delete the Precision X but I still have Armory crate which controls the rest of the computer. The last thing I did was cable rotation

after 6 hours just got my 1st black screen, had to hard reboot.
 
going to try and stop all asus background services. see if that helps.
 
edit:
I forgot to mention, I thought it may have been my Seasonic prime px-850 that was the issue.
So I bought a Corsair Hx-1000 to test but still the same, random black screens.

if this issue is also the same one involving Display driver nvlddmkm stopped responding; the only solution I found was to disable hardware accelatio non any software you have open like chrome and vlc. percision X1 also needs to be closed (system tray is fine).

Hi eveyone,
I have :
GPU: EVGA 3080 FTW3 ULTRA
CPU: i9-10900KF
Motherboard: ASUS PRIME Z490-V
RAM: 3000, xmp
PSU: Corsair 850
Operating System & Version: Windows 10 home, up to date
GPU Drivers: 465.89 game ready drivers
Screen : HDMI 2.1 connection to TV, 4k 120Hz setup
 
When I first power on the system, bios flash screen shows up then signal is lost. If I wait long enough I get black screen and nothing to do but reset. If I reset after with the reset button when it's power on, second time and subsequent resets it works. But every time first bootup (power on sequence) is not sending correct signal and ends up with black screen.
This started to happen after I did update Bios, GPU Bios and Nvdia drivers for ReBAR support.

Hi

I have this issue every time I use display port or HDMI. Sometimes when I start a game the monitor disconnects and sometimes when I start the pc I don’t get any signal. I’ve tried everything from DDU to factory resetting my pc reinstalling all drivers. I have an ftw3 3080 ultra and Corsair sf750 psu. Should I rma my card?

Have a 3080 FTW card that was working just fine for a couple of months. Then I moved my tower, and when booting back I forgot to plug in all 3 PCIe cables back into the GPU. When booting, there wasn't a red light on the GPU itself, and instead just nothing happened on the boot up. I powered down, plugged into the 3rd PCIe cable, and now can't get my card to output a signal to the monitor.
 
I have confirmed this is a GPU problem, as I have tried the card in two different towers with multiple monitors and multiple cables. Also, I have tried a different GPU in each tower, and it works just fine, so I am nearly certain it's the 3080 causing the issues. 
 
When I boot up the 3080, the GPU LEDs turn on, and the fans spin just fine, but the card is just not detected on the Motherboard. (There is a red light on the MB indicating that bad hardware is installed, and I removed my ram and put it back in trying to fix this, but the red light persists, so I am pretty sure it's the GPU causing it.) I have tried multiple PCIe slots, have tried a cmos reset on the motherboard, and uninstalling/reinstalling nvidia drivers. Nothing works to get this card to output a signal through either HDMI or DP. 
 
Does anyone have any recommendations of other things I could try to attempt to get the card working again and output a display to my monitor(s)? 
 
Thanks

I'm old enough to remember when you just plugged in a video card & it worked.