When I installed the new version of the folding software, Which I had to install to a new sub directory. The web client worked fine then when I restarted my PC it did not work anymore is there any way to fix this? It just loop refreshes with nothing showing, the regular client works fine.

Chrome doesn't like it but you should be able to open it with explorer. 

I found a fix but I think you might have to use it every time you run the client.. Press F12 Key then right click the refresh button and select hard reload (or ctrl+shift+R). This will work for chrome browser.