You could try setting Speedfan & your NZXT software to Not start with Windows & reboot.  Then see how PX1 reacts.  Does PX1 start working as you'd expect.  If so, then you know one of those other programs is conflicting.  Start one of them at a time to determine which one it may be.

CAM and Precision (and other software) have a history of sometimes not playing well together.

In Precision, the clickable "AUTO" button in the "FAN SPEED" section must be lit or fans will remain at a fixed manual speed..In the fan curve section, "Fan Curve Control" must be clicked on for fan control to be handed off to Precision instead of the card.

Always click "Apply" after making any changes.

I have actually found a "solution".
 
So, after uninstalling NZXT CAM and restarting. I thought what the hell lets just fire up HWinfo and see what is actually going on here. Turns out that now, the gpu *IS* actually following the curve I have set, as reported by HWinfo, however the PX1 software has the numbers locked at zero, so apparently that is a visual bug in the software I actually am getting the right response now even though the software still seems borked, but this brings up another question.

I'm not sure if this is the right place, but since I no longer have that stupid NZXT CAM software to set my pump speeds is there some way I can lock it at 100% through the bios?
It connects through a 3 pin fan-type connector into a 3 pin header which in the manual for the AIO is labeled "pump tachometer" but from what I know about headers is that not addressable since it does not have the 4th PWM pin?
or is it treated like a 4 pin fan that is connected to a 3 pin header and runs at 100% no matter what?
will the RPM's for the connected pump be read in my BIOS through that header as if it were a fan and be accurate?
at this point I could care less if I can control it through a curve or not if I can just have it run at 100% all the time that's fine with me.
 
I apologize for all the questions, thanks for the quick responses.

I have an old Fatal1ty Z97 Killer mobo, and actually I was looking in the BIOS and was having trouble trying to get the pump to be controlled and work, but I did find a solution that I wanted to post here incase anyone came across this through a google search or through the forums that was having a similar problem. I still have issues with Precision X1 going completely fubar and not working at all for fan control, NZXT CAM is still totally screwed when it comes to controlling my pump, but I have an answer!
 
 
************   SOLUTION:   ************
 
   
Every program I tried for fan control was NOT working correctly, until I found this one. It is a custom software written by one guy and it is so incredible I have to share. Download this software called FanControl (I hope it's okay to post links, please don't get mad at me mods!)  It is a PHENOMENAL fan control program and completely solved all of my issues. I was able to set custom controls with custom curves for each separate header, it was able to see and control my AIO pump that I connected to my header and it realized that it was a pump and it optimized that accordingly. It has a vast set of customizable options and best of all, it overrided every other program I had and everything worked perfectly after that. I now uninstalled SpeedFan, NZXT CAM, gave up on BIOS config, and solely use just FanControl. I can't share enough how much that program saved my sanity.
 
**Edit: Apparently I am unable to post links, if you google FanControl the creator's name is Remi Mercier you can find his program on github and other places. The latest release as of 9/5/2020 is V48.
Mods please let me post links so that others can find this, I am in no way affiliated with the creator or sponsored by him I simply want to help spread the word about this amazing guys' work.
 
Hope this helps future people, you have a wonderful day! :)