https://gamingbolt.com/nba-2k21-shares-first-footage-of-current-gen-version-pc-requirements-revealed
 
When it comes to NBA 2K21, a lot of the conversation is centered around the next generation version, especially the price hike and whether that is justified or not. But the game is also coming to current generation consoles, and today we got our first look at that version, as well as the PC requirements for the game. The PC version is actually based on the current gen version of the game, so as you can imagine they aren’t too demanding and pretty on-par with last year’s title. As a minimum you’ll need an Intel Core i3-530 or AMD FX-4100 with 4GB of RAM and NVIDIA GTS 450 or the AMD HD 7770 for GPUs. Maximum bumps that up to an Intel Core i5-4430 or AMD FX-8370 with 8GB of RAM with NVIDIA GTX 770 or an AMD R9 270. Both minimum and maximum require 80GB of space. You can check out the footage below.
 
NBA 2K21 will release September 4th for PlayStation 5, PlayStation 4, Xbox Series X, Xbox One, Switch, PC and Stadia.
 
Looks to me like most any system can handle the recommended requirements. 
 
MINIMUM:
OS: Windows 7 64-bit / Windows 10 64-bit
Processor: Intel Core i3-530 / AMD FX-4100
Memory: 4 GB RAM
Graphics: nVidia GTS 450; AMD HD 7770
DirectX: Version 9.0a
Network: Broadband Internet connection
Storage: 80 GB available space
Sound Card: Directx 9.0x

RECOMMENDED:
OS: Windows 7 64-bit / Windows 10 64-bit
Processor: Intel Core i5-4430 / AMD FX-8370
Memory: 8 GB RAM
Graphics: nVidia GTX 770; AMD R9 270
DirectX: Version 9.0c
Network: Broadband Internet connection
Storage: 80 GB available space
Sound Card: Directx 9.0c