EVGA

Project 11715

Author
Post
Essentials Only Full Version
HaywireHaywood
SSC Member
  • Total Posts : 860
  • Reward points : 0
  • Joined: 2018/05/13 10:32:58
  • Status: offline
  • Ribbons : 2
2018/09/09 06:16:37 (permalink)
Was looking at what one of my GPUs was folding and found this.  Pretty interesting and I am glad that they are looking for ways to make the whole thing more efficient.

Project 11715

Disease Type: Unspecified
This project is generating a test set for what we hope will increase the power of F@h by orders of magnitude, i.e. adaptive sampling. The idea is that instead of running many trajectories for a long time and seeing what happened at the end, we will run hundreds of trajectories for just 1 to a few gens - then pick frames from those that have advanced most on a given goal function (e.g. traveled furthest from their starting structure and closest to a target structure) and re-seed the next hundred of trajectories etc. - there’s a good amount of literature showing this can achieve very significant speedups. It will also let us make the same conclusions with much less data - speed the whole process up.
11715 is a short designed beta-hairpin peptide - trpzip2, which has unfolded, folded, and mis-registered states - i.e. it’s a good model of what we have with our cancer proteins where multiple conformational states have to be connected. We’re collecting ‘standard’ reference data here, and then will try our adaptive machinery for the first time to try to reproduce the ‘standard’ results.
post edited by HaywireHaywood - 2018/09/09 06:17:46


Heatware Affiliate code: QLF0RY1CK9
#1

10 Replies Related Threads
    bcavnaugh
    The Crunchinator
    • Total Posts : 38977
    • Reward points : 0
    • Joined: 2012/09/18 17:31:18
    • Location: USA Affiliate E5L3CTGE12 Associate 9E88QK5L7811G3H
    • Status: offline
    • Ribbons : 282
    Re: Project 11715 2018/09/09 11:14:36 (permalink)


    Associate Code: 9E88QK5L7811G3H


     
    #2
    Teknogroovie
    Superclocked Member
    • Total Posts : 217
    • Reward points : 0
    • Joined: 2018/05/23 17:19:38
    • Location: Cental, IL
    • Status: offline
    • Ribbons : 0
    Re: Project 11715 2018/09/09 11:16:58 (permalink)
    Yeah one of my 1080ti, runs that allot.  It does kill the PPD by about 200K but glad to see they are running test to improve the efficiency and who know's what else they may discover in the process.     

     My Affiliate Code: LR3I6SS70W 
     
    #3
    Cool GTX
    EVGA Forum Moderator
    • Total Posts : 30996
    • Reward points : 0
    • Joined: 2010/12/12 14:22:25
    • Location: Folding for the Greater Good
    • Status: offline
    • Ribbons : 122
    Re: Project 11715 2018/09/09 13:52:41 (permalink)
    Interesting -- I've seen those running over the last week or so --- they were giving poor PPD

    Learn your way around the EVGA Forums, Rules & limits on new accounts Ultimate Self-Starter Thread For New Members

    I am a Volunteer Moderator - not an EVGA employee

     https://foldingathome.org -->become a citizen scientist and contribute your compute power to help fight global health threats

    RTX Project EVGA X99 FTWK Nibbler EVGA X99 Classified EVGA 3080Ti FTW3 Ultra


    #4
    bcavnaugh
    The Crunchinator
    • Total Posts : 38977
    • Reward points : 0
    • Joined: 2012/09/18 17:31:18
    • Location: USA Affiliate E5L3CTGE12 Associate 9E88QK5L7811G3H
    • Status: offline
    • Ribbons : 282
    Re: Project 11715 2018/09/09 18:10:53 (permalink)
    Cool GTX
    Interesting -- I've seen those running over the last week or so --- they were giving poor PPD


    Even So You Are Back on Top Link

    Associate Code: 9E88QK5L7811G3H


     
    #5
    notfordman
    Omnipotent Enthusiast
    • Total Posts : 10345
    • Reward points : 0
    • Joined: 2007/08/09 23:52:23
    • Location: In a van, down by the
    • Status: offline
    • Ribbons : 28
    Re: Project 11715 2018/09/10 10:43:04 (permalink)
    Glad you brought that up Haywire, it's definitely interesting. Thanks! I noticed I was getting those quite regularly. 

    Heatware : http://www.heatware.com/eval.php?id=68330
     
     

    #6
    planetclown
    FTW Member
    • Total Posts : 1692
    • Reward points : 0
    • Joined: 2010/03/02 07:59:51
    • Status: offline
    • Ribbons : 15
    Re: Project 11715 2018/09/13 08:57:46 (permalink)
    notfordman
    Glad you brought that up Haywire, it's definitely interesting.


    +1, very cool!  This article explains adaptive sampling a bit more.  https://www.seas.harvard.edu/content/breakthrough-algorithm-exponentially-faster-than-any-previous-one

    EVGA Associates code: OLY2307BPM0MXZU Click for a discount on your next purchase from EVGA.com


    #7
    Cool GTX
    EVGA Forum Moderator
    • Total Posts : 30996
    • Reward points : 0
    • Joined: 2010/12/12 14:22:25
    • Location: Folding for the Greater Good
    • Status: offline
    • Ribbons : 122
    Re: Project 11715 2018/09/13 10:03:15 (permalink)
    planetclown
    notfordman
    Glad you brought that up Haywire, it's definitely interesting.


    +1, very cool!  This article explains adaptive sampling a bit more.  https://www.seas.harvard.edu/content/breakthrough-algorithm-exponentially-faster-than-any-previous-one


    Nice easy read, thanks for sharing

    Learn your way around the EVGA Forums, Rules & limits on new accounts Ultimate Self-Starter Thread For New Members

    I am a Volunteer Moderator - not an EVGA employee

     https://foldingathome.org -->become a citizen scientist and contribute your compute power to help fight global health threats

    RTX Project EVGA X99 FTWK Nibbler EVGA X99 Classified EVGA 3080Ti FTW3 Ultra


    #8
    bcavnaugh
    The Crunchinator
    • Total Posts : 38977
    • Reward points : 0
    • Joined: 2012/09/18 17:31:18
    • Location: USA Affiliate E5L3CTGE12 Associate 9E88QK5L7811G3H
    • Status: offline
    • Ribbons : 282
    Re: Project 11715 2018/09/13 10:35:43 (permalink)
    Cool GTX
    planetclown
    notfordman
    Glad you brought that up Haywire, it's definitely interesting.


    +1, very cool!  This article explains adaptive sampling a bit more.  https://www.seas.harvard.edu/content/breakthrough-algorithm-exponentially-faster-than-any-previous-one


    Nice easy read, thanks for sharing


    +1 BR for Post #7

    Associate Code: 9E88QK5L7811G3H


     
    #9
    Cool GTX
    EVGA Forum Moderator
    • Total Posts : 30996
    • Reward points : 0
    • Joined: 2010/12/12 14:22:25
    • Location: Folding for the Greater Good
    • Status: offline
    • Ribbons : 122
    Re: Project 11715 2018/09/13 11:14:27 (permalink)
    Done BR awarded

    Learn your way around the EVGA Forums, Rules & limits on new accounts Ultimate Self-Starter Thread For New Members

    I am a Volunteer Moderator - not an EVGA employee

     https://foldingathome.org -->become a citizen scientist and contribute your compute power to help fight global health threats

    RTX Project EVGA X99 FTWK Nibbler EVGA X99 Classified EVGA 3080Ti FTW3 Ultra


    #10
    bcavnaugh
    The Crunchinator
    • Total Posts : 38977
    • Reward points : 0
    • Joined: 2012/09/18 17:31:18
    • Location: USA Affiliate E5L3CTGE12 Associate 9E88QK5L7811G3H
    • Status: offline
    • Ribbons : 282
    Re: Project 11715 2018/09/13 11:19:26 (permalink)
    Might be about the same Subject Matter in a since on the BOINC Side.
    post edited by bcavnaugh - 2018/09/13 11:20:54

    Associate Code: 9E88QK5L7811G3H


     
    #11
    Jump to:
  • Back to Mobile