Updated to 6.1.16, have been running 6.1.15 previously with no issues.
 
Playing IL-2 Battle of Stalingrad in VR with Oculus Rift.
First thing I noticed, was my GPU info was not only showing on PXOC but after launching game was showing up on my monitor ( not on Rift HMD, just the mirror image on the monitor). 
Then shortly after IL-2 would stop responding and close. Tried it several times, and it happened each time.
 
Uninstalled PXOX 6.1.16, and deleted folder contents. Installed 6.1.15, and no issue whatsoever. No GPU info displaying on mirror image on monitor, no game crashes.
 
I do use a custom fan curve, do not use the OSD.
I will stay with 6.1.15 as it has been working great for me, just thought I should bring this to someone's attention. 
 

I need some help please!!
 
Ok so since going back to 6.1.15 I have been running fine, many hours gaming in VR without a single issue.
All of a sudden today, now 6.1.15 is doing the same darn thing as 6.1.16 did to me in my original post above. I load up Battle of Stalingrad and launch it in VR, the GPU info is now showing on my monitor again ( not in my Rift), which it never does, and when I launch the game shortly after I get a game crash before I even get to select any items in the game  menu.
 
I tried closing out Precision XOC and starting it up again, event tried a PC-reboot all to no avail. Now it is behaving exactly like it was when I tried 6.1.16.
What has happened, why is it doing this?
I need Precision XOC for my 1080 Ti FTW3, and now it is rendering my game useless?
 
I guess I could try a complete uninstall and a clean new install of PXOC ugh...
 

Good to hear you got it resolved.  For the moment anyway...

So I thought I would update this thread, here in the last couple of versions of PXOC this problem appears to have completely gone away. Not sure if installing outside of the program files folder helped or not, or just newer version.