What are your full system specs? What is the make/model/age of your power supply? Have you tried to do #4 listed here? If yes, did it stop the tdr error?

i7-4790K @ 4.00GHz
Asus z-97a mobo
16gb DDR3 1866MHz hyperx fury ram
Corsair HX1000i that I ordered in november of last year
and I run my OS off of a Samsung 850 EVO 250GB SSD.
I have tried using EVGA Precision XOC to underclock my gpu from a range of -50 to -200 and and anything past -100 will freeze and crash my pc to where I have to physically power down. I previously ran EVGA 980 ti Hybrids in SLI without issues. thanks for the response by the way!

Some things to try...
 
#1 See if the problem persists while running the other vbios on the card.
#2 Test the card in another pci-e slot.
#3 Try powering the card with a different pci-e cable. Try different outputs on the psu. Try powering the card with two pci-e cables instead of a single cable.
#4 Run the 8k optimized preset on unigine superposition to see if you get the same crash.

HuggiBear
Alright, I'll give these a run tomorrow and let you know, Thanks!

Thanks as we'd like to know if the suggested solutions work. 

HuggiBear
Hey guys, got home late and didn't want to mess with the pci-e suggestions tonight. I also don't quite understand what you mean by running the other bios on the card if you could give me some further details, ik, i'm a nub. I did however run the unigine superposition on 8k optimized and it did so without a crash. (btw this is the benchmark I was using that would crash every time when I was testing underclocking my gpu) 

Glad to hear you're not crashing at this time. You can see the vbios switch selector in the following pic...
 

 
Master vbios has a 117% power target, while the slave vbios has a 127% power target.
 
 

No need to switch to the other vbios since you crashed on both. When underclocking the card did you only underclock the core?

Set the memory clock to -502 and see if you crash or not.

Run it a few more times to see if you can get it to log nvlddmkm.sys as the problem. Make sure you set the memory back to -502 on each run.

HuggiBear
Does it matter what application I crash on?

Use pubg.

Does the nvlddmkm.sys error show up pretty much constantly if you run the card at stock clocks? If yes, it's definitely looking like a card issue as reducing the memory clock to -502 made the nvlddmkm.sys error not show up as much. 

Yep, running fine in multiple other applications, and crashing in another is a dead giveaway that the card is unstable. Let us know if suggestions #2 & #3 posted in post #6 help fix the problem.

I am running 0501....but i probably should have that updated. I'm about to try the pci-e suggestions.

There is a known crash issue involving Unreal  4 and games built with it when run on nvidia drivers.
 
https://issues.unrealengine.com/issue/UE-40824

HuggiBear
I feel like i've tried it all and then some and i'm still crashing on 80% of the games I used to play. I was overly excited when I had found out I was sent in a 1080ti ftw3 hybrid in place of my 980ti hybrid but now I can't even play 5 minutes of a decent game.

As a suggestion, have you tried running without Precision installed? When you get it to run correctly the 1080 Ti is  great card.  I am assuming you have updated the BIOS of your motherboard?
Are you running your system fully UEFI or with CSM enabled?

Hi all.
 
I have very similar problem on GTX1060, but I get this faults only if I use internet browser (MS Edge, Firefox). So in Idle mode. Without any BSOD, or another crashes of OS. PC is very stable also in games. No problem found by Memtest or Windows Memory Diagnostic Tool after several hours of testing.
It started from Windows 10 Creators Update 1703 and is still there on Fall Creators Update 1709. Errors are very random and they cannot be predicted or simulated (may not occur for several days).
 
 
LKD_0x141_Tdr:6_IMAGE_nvlddmkm.sys_Pascal_3D
LiveKernelEvent 141
 
PC Specs:
GPU: EVGA GeForce GTX 1060 SC 6GB (06G-P4-6163-KR) - BIOS 86.06.39.00.60
CPU: Intel Core i7 4771@3.5GHz
MB: Intel DZ87KLT-75K (using Legacy Boot mode)
DDR: Corsair 16GB DDR3 1600MHz CL9 (2x8GB)
HDD: Samsung SSD 850 EVO (SATA3)
PSU: Corsair RM650
 
 
Please, tell me, how can I test where is the problem. Between majority version of Windows a I made clean installation. I use always latest stable drivers from NVIDIA.
Thanks.