Hi All,

I've got a 7980XE, x299 FTW K (1.23 bios), 32gb DDR4 of some irrelevant ram, EVGA gtx1080 sc, Samsung 970 Pro M.2, Win10 Pro 1909.

I'm getting random blue screens, consisting of CRITICAL_PROCESS_DIED, UNEXPECTED_STORE_EXCEPTION and a few others I've seen, I suspect these are due to the M.2 drive dropping out somehow or the connection getting corrupted. On the last boot it refused to load windows as the drive was gone completely, I disconnected the power and verified that the drive was in the slot properly etc. I've already changed the PSU which I initially suspected due to the wide ranging nature of the bsods, it could only be psu, cpu or hdd and I don't suspect the cpu tbh. I ran a ram test and it passed with flying colours after ~6hrs. I've run cpu stress tests for quite a while with prime95 and hit no errors. Any reason why this would be happening? The drive seems to be secured in place properly with the small screw provided so it can't be falling out or making contact with the board itself, the standoff is fine ...

I'm really at my wits end trying to fix this, what else can I do to diagnose or fix this?

p.s. no overclocks

What are the other bluescreens you have been seeing?

Bepzinky
Check your Windows event log...WHEA galore?

Nah fixed those by correcting the voltages and ram speeds. I did have these but the x299 whea post by puget systems fixed it (I can't link it here).
 

Sajin
What are the other bluescreens you have been seeing?

I've also seen an IRQL_NOT_LESS_OR_EQUAL, KERNEL_DATA_INPAGE_ERROR, DRIVER_POWER_STATE_FAILURE. These are much, much less frequent, i.e. the kernel data i've only seen once.

bdary
A couple things you could try.
 
Move the NVME drive to a different slot & test.
Install Windows on a different drive to see if the issue goes away.  That may point you in the right direction.
That's all I got...

I can move it to the second m.2 slot, is that gonna be fine if I set it to boot off that, should work as in the first slot?

Assuming the drive is functioning as it should, you should be able to boot from any m.2 slot for your NVME drive.