I just though of this other day, and I think I should share it
behold X79 mITX - Quad Channel - up 12 cores Ivy-EP support
 - PCIe 3.0 16
 - 3 Intel NICs
 - 6 rear USB 3.0
 - laptop DIMMs
 - Support up to DDR3 2133 (O.C) 32 GB Non ECC/ Unbuffered RAM
 - built-in nVidia 730M for basic monitor support
Artist's Render (In this case, me)


Supposed Configuration

@lephron
I actually used laptop DIMMs, for my 3D version of X79 mITX, I would prefer not to put the laptop DIMMs under because the space between some cases and the motherboard isn't large enough to put these 32GB of goodness. Actually, I designed this board for bragging/serious powerhouse/server/record breaker for having the most power in smallest board, I knew that the narrower version already existed, but I didn't use it because I tried it, and full sized DIMMs were too much, that It didn't have space for chipset and USB 3.0 and SATA 6 Controllers. but thanks for suggestion

Oh dear, I think I'm having crazy ideas today with my Sketchup.
C602 mITX(Server) Red - SATA III, Black - SATA II, White - SAS 6GBps. Up to 26 drives. RAID 0/1/5/10 support
Linux/Windows compatibility
Up to 200W CPU support.
Built-in Intel HD 4000 for display.
Separate Audio Needed
 

So mounting single-sided DDR3 SO-DIMMs like this wouldn't have worked on the solder side with enough distance for typical standoffs?  I'd probably sacrifice a lot of make it work, lol.
 

 
It is very different from vertical SO-DIMM connectors which are actually much thicker than you have it:
 

 
Chipsets sure take up space, though I'm pretty sure in the future, the pure CPU and APU types will evolve into SoC's where all chipsets are in the same die as the CPU x86 packages.  This would/should enable smaller high-end form factors.  But while Intel put voltage regulators in Haswell, motherboard manufacturers still put more on the board to justify the unnecessary heatsinks surrounding the socket of most LGA1150 boards.  There is technically no need for them, which could save even more space, at least if you weren't overclocking.

I have to say your nano-ITX LGA2011 is absolutely gorgeous, if really wish it were an option, even if the board itself were $600.  Although I'd make/request changes to the layout at the risk of upping the value.

1. I'd still opt for placing the SO-DIMMs on the back, I don't do mid-term upgrades so lack of easy upgrading is mute.  I'd install once and leave it that way for years, except to clean for dust.
2. I'd eliminate the PCIe slot altogether and opt for an External PCI Express port on the I/O side, so I can connect up to one x16 card externally per port.  Though the x16 ports are bigger than the DVI ports, and deeper than 6-channel audio ports; multiple will require a bigger board and ironically have room for embedded PCIe x16 slots.  
3. As for I/O, I'd only need Ethernet with no video ports.  If having the External PCIe, then I can connect any number of whatever add-in cards I need.  Or through Ethernet, have an array of boards connected in a cluster.  
4. I'm on the fence with USB and audio ports in I/O since those pins will be embedded in the board anyway; so for me, it would be either one or the other.  Though I prefer less I/O ports visible and/or laid out in a flat profile.  I love the clean and empty look, it becomes prime candidacy for smaller form factors.  I couldn't careless how thick the PCB ends up, whether they are 16-layer or 20-layer; if I was actually in the market for something like this, I'd be in "spared no expense" mode.  You know, whatever needs to be done.

But the only way LGA2011 can get smaller than nano-ITX would probably require soldering and removing the socket.  Here's an example of picoITX, it is ridiculously tiny-- although an Ivy-EP 12-core would take up one-third of the board space while the chipset and I/O takes the other.  I don't think there is room for four SO-DIMMs, on either side, unless high-density RAM chips themselves were soldered on.  Cooling for small boards are debatable, while vapor-chambers are more effective in SFF since they are used in graphics cards but not in CPU tower-based cooling, a custom motherboard waterblock isn't far-fetched. 
 
Although a Haswell quad-core or upcoming Broadwell quad-core would definitely be small enough to still allow SO-DIMMs, since you only need two; but then you need at least a mini-DisplayPort for the IGP.  Screw the larger traditional VGA, DVI, and HDMI ports.  But do keep an Ethernet and external PCIe port, or find a way.
  
I'm all for beating stereotypically and generally accepted form factors into the ground, I don't believe high-end has to be big.  So thank you, drchoi21, for entertaining me and I'd like to think it was mutual.

Wow it would be amazing to make a super powerful mITX build with that Shuttle board.

no, all mATX motherboards have perpendicular RAM slots

 The RAM/DIMM slots parallel to the PCIe slots looks better and is more tidy layout, even the 24 pins connector must be parallel to the slots

http://www.overclockers.co.uk/showproduct.php?prodid=MB-102-AK
 

drchoi21
no, all mATX motherboards have perpendicular RAM slots