Version 6.0.9 is pretty smooth. I like it best so far. However, it has introduced screen flickering in Diablo 3. It shows up in a vertical column in the left edge of the screen. It goes away if I close PrecisionXOC. 
EVGA GTX 1080 FE
NVidia Driver 375.95
 
 EDIT-
 
Fixed. I had checked FCAT Overlay in OSD Settings. Disabling it fixed the flickering in D3.