To manually run it, you have to hit click on the
yellow > right above the word APPLY. After that click right two times on basic to get to manual and the run button will be enabled. What I don't get is that PXOC defaults to basic with the run option being disabled, but somehow it randomly opens and runs.
Also if you click on the cog wheel/settings button when you're in the OC scanner, you will be able to pick your resolution, AA etc