Another, 'been running my X58 for ages, time to update..' builds coming on here.
 
Current plan is for the X99 Classi (not that I'm in a rut) with a 5820k perched on it with either 16 or 32 of Crucial or GSkillz with it.
Case will be mid or small full tower, it'll probably get a single spinning disc (maybe external), an optical drive and one of the Plextor 1T Pro SSD drives.  Other than that it'll get a single GTX 970 FTW+ and not much else in the box.
 
Speaking of cases, the Fractal Design R5 caught my eye with Hardware Canuk's review (last years?) with the bottom screen filter.  That *is* kind of important as the mudball... err .. wonder puppy that is my dog remains stalwart in his efforts to bring the outdoors inside.  Drives me nuts somedays but..
 
Cooling is on my mind.  I'm liking the db and cooling (for air cooled) of the .  The other side of that coin is going with the closed coolers like the NAXT Kraken X60 (or X61?) or CORSAIR Hydro Series H100i seems to gain on the cooling with some payment in greater decibel levels.  I'm not planning on putting cooling on the GTX anytime soon, maybe after the warranty period is over.  
 
If I'm really lucky again, it'll be another five years before I have to do much to this one.
 
Thoughts on cases, cooling pros and cons would be appreciated, especially weight limitations for CPU coolers on the EVGA X50 series MBs.  (I didn't find a mention in the X99 manual in the CPU/CPU Cooler section of weight limits.)
 
TIA,
 
Nick

Personally, I'm using the H105.  I'm not entirely sure how much better it is than an exceptional air cooler since I've never had anything else on this chip.  That being said, the ease of installation and clean look inside the case are both pluses for me over air cooling.  The performance of it is no where near a custom loop, but unless you're planning on trying to OC very high, I don't think you'll have any issues.  It all but eliminates clearance issues in your case unlike a huge heatsink.   Just make sure the case you choose can handle a 240 radiator.
 
I find that the included fans with the Corsair AIO's are indeed loud.  I'm going to switch them out for some Noctua fans here shortly.  I keep my case on the floor next to my desk so it's not intolerable.  If the case were sitting on my desk it would be another story.  Keep in mind that the fan noise only becomes an issue when spinning at higher rpms.  At 50% speeds and below they are not an issue at all.
 
Case-wise I'm running a HAF 932.  This is a carryover from my X58 system.  The case has worked well for me on both builds and offers really good air circulation and room inside to fit later upgrades.  You did mention dust filters, so I'll warn you that the HAF has none.  They do sell kits for them online though.

Corsair Vengeance LPX 32GB (4 x 8GB) DDR4 DRAM 2400MHz C14 memory kit for DDR4 Systems (CMK32GX4M4A2400C14) Works Great @ 2400MHz and the CPU @ 4500MHz, this is low profile memory.
Also take a look at this case for $199
    Nanoxia Deep Silence 6 Gigantic Tower Case Fits HPTX Motherboard, Large Water Cooler Ready, with 8 Fan Controllers, Air Chimney - Black WOW! Now 292.45 Prime, I got mine just in time.
Sound Padding in this bad boy.

 
Watch the Video.
 
My mods to this case, more photos here: https://www.flickr.com/photos/48137161@N00/sets/72157650071221240/

 
I removed the 10 Drive Bay unit for a Radiator in Push/Pull

Switnick
BC,
    I was back and forth enough on the memory, I had to go back and check the invoice to see what I did order.  The fangy looking GSkillz MEM 4X8G|GSKILL F4-2400C15Q-32, but at least it is black.  
 
    Sitting under the desk with no window, the lights and colors thing is a little wasted on me.  :)

Is it low profile memory?

Ung...
... Gah..
... ... .. Arghhh...
 
Okay, this could be going just a little smoother, however, before I dive off into the angst of my 'progress', I'll play a little catch up on BC's and Jack's comments 'n questions.  Not that either are not germane.  Come to think of it, it'll be a nice segue. 
 
BC, no, the Gskillz is not low profile.  They are, however, *almost* low enough to allow a top mount for the Corsair H110.  But only *almost*, as in, "No, that will not work.", kind of *almost*.  (I could learn to hate that word.)
 
Jack, that Entho is pretty neat looking.  Pretty huge.  Pretty heavy.  Neat.  Plenty roomy.  But it lacks a coffee maker.. and for $479 (Newegg) it had better!  :)  In comparison, the Define R5 was right at $150 including the WA state tax from the shop just down the road.  But, the Entho's size does have a benefit.. as in the tale following.
 
So, the final build parts list, carefully selected to mate, match, compliment and gain from the reading of others experiences.  Maybe, just maybe, a bit more MUTUALLY compatible would have been a better target.  There's a LOT of *almost* to follow.  The choices and some rationale on the choices follow.
 
PSU:  I went with a Corsair 860i.  It's quiet up to the middle of its load range, per reviews at least, and is hitting its peak efficiency in that realm.  My 'as built' load put me comfortably under 400 (~370 by memory) so there's some headroom for clocking this thing a bit and some expansion.  This puts me in a comfy spot.  The length, its a little more than I'd like, as the Define R5 will take a 280 length radiator if the length of the PSU is around 170mm.  This thing is 185-ish.
 
Cooler:  The 280 radiator of the H110 was a draw for me, a lot of cooling potential with big (140mm) quiet fans which *should* be just turning easy, if at all, for most of my uses.  
     Okay, so doing fit checks I find that with the PSU sitting in place, there just isn't room on the bottom of the case for the H110 radiator, much less any spare room for any PSU cables to actually plug into said PSU.  For the H110, the base location is a bust anyway as the hoses are way to short to get the pump on the CPU.  
    Moving on to the top location, there is good room for the width of the radiator and length is okay with the back fan removed and the Optical disk drive bay left in place.  However, as noted to BC above, the top of the heat spreader on the Gskillz keeps the radiator mounting holes from lining up.  It needs another millimeter (that isn't there) to clear.  Hose reach is good.  Really though, having the radiator top mounted wasn't my favorite choice mostly because the removed vent covers would be letting noise out and dust in.  Please note that there's a long haired mud magnet of a canine nature that donates dust and doghair in an impressive manner.
     That left the front.  Understand, the Define R5 has a very nice screened front covering a fan bay that takes a pair of 140 mm fans nestled snugly together.  The formed inner face of this bay is threaded at the four corners of the fans to allow long screws (supplied) to pass through the front mounted fan and thread into the inner surface of the fan bay.  Slots in that inner bay surface complete the options list for radiator and/or fan mounting.  The H110 has threaded holes on each face of the radiator to allow a screw to be threaded in.  There is no provision to allow a screw to pass through a gap in the radiator fins.  
      Installation, on the front is currently some motherboard screws (gots to have a stash) threaded thru the threaded fan bay holes and engaging the threaded radiator holes on one four-hole pattern and two more screws through slots in the fan bay base, the remaining two holes on the radiator unused.  Remember the nice arrangement of the 'snugly fitted 140mm fans in the case fan bay?  The H110 mounting leaves something like 4 - 5 mm space between the two fans.  The case and the radiator holes do not line up.  The only option left would be to drill the threads out of the upper four holes to allow the radiator mounting screws to pull up only on the threaded holes in the radiator.  If I was to continue with this case, that would be my next step.
 
    So, the radiator has finally found a home, of sorts, on the front of the case, hoses toward the top of the case which seems should allow the pump to mount on the CPU.  Both HDD bay caddies are removed.. and really, it'll be crowding the PSU cabling to mount one of the bays on the bottom of the case between the radiator and the PSU... using the stock mounting slots at least.
 
   With the fit checks done on the H110, I started to install cables.  As mentioned in a couple of case reviews, the 8-pin CPU cables do not quite go through the grommeted slots at the top of the motherboard tray.  The Corsair cable ends do unclip to allow you to pass two thinner halves through to be reassembled.. pretty easily.  This is not a show stopper, nor is it really that much of a delay.
 
   I started to run into little access issues as I cabled up the X99.  The 24 pin, I had to come in from behind the optical bay for a shot at the motherboard.  I couldn't come through the intended motherboad tray grommet as it was way too close to the 24-pin motherboard connector to come through, turn and connect.
 
   Things did muddle along 'okay' until I came to the USB 3.0.  On the X99 this is at the bottom edge of the board and faces the bottom of the case, unlike the USB 2.0 pointing away from the motherboard sitting just left of the 3.0.  In the Define R5, the motherboard tray slopes up from under the motherboard and.... and does not let the 3.0 cable end line up.  Alignment of the cable end and the motherboard connector is no better than 20 or 30 degrees out of alignment, it just won't go... well, as long as you don't want to pry chunks off the motherboard.  (Nor do I use hammers when connecting puter stuff...)
 
    As you might guess, I said, "Darn."
    Digging back through manuals and specs I found the curse of inattention, or perhaps the curse of target fixation on cooler fitment, at best??  
    The X99 Classified, is eATX, the Define R5 is ATX or mATX.  It is nearly eATX... *almost*.
 
    So, the options.  Off to the store tomorrow to see what case I can dredge up, call up Newegg and see about an exchange for a different MB.  Tending toward the case option at the moment, but for now, I'm a gonna go see about an adult beverage..
 
    Mind the small print kids.  
    ... and the not-so-small print too.
 
   Nick

So far this morning I've been looking at alternatives, mostly in the realm of cases.  Fractal's R2XL will take the eATX but the front hinged door is on the wrong side, which is compounded by the office set up.  I'm really not wanting to reconfigure the room for a computer case door.  (One thing I like about the R5, the door is quite readily reversible.)  
 
Quiet, cool, dust control are all concerns and about of equal consideration for me.
 
So, the other alternative is to put a smaller board in there.  Staying with the EVGA, that would be the X99 Micro.  At a glance, it drops memory slots to 4, a single LAN, none of the M2 slots, changes to the Realtek sound, no BIOS switching option, generally trimmed down.
 
Is it trimmed down 'too far' or is this going to be enough MB to take a little OC and what else I thro at it??
 
*back to the headache..*
 
 

I have the X99 micro EVGA and there is a m.2 on it not sure what you mean with "none of the M2 slots"
 
not really sure what job you do but for a working computer i doubt you will ever need to switch bios (honestly i don't need to switch bios at home either i OC stable and then keep it like that)
 
4 slot memory allow you 32gb (like in my setup) i know of few application that really need more memory then that
 
as on board sound is enough unless you are a pro in that case you will need a sound card anyway i am using a Asus Xonar STX (i made a post on how to make it work on X99 since is kind of buggy)
 
the only real grip is the single LAN that is definitely a shortcoming  
 
OC wise my X99 micro keep an easy 4.3mhz on i7-5960X @ 1.27V (daily use)
i pushed it at 4.5mhz but i had to raise the volt at 1.35 (and it's not really worth for daily use)
 
obviously is water cooled i think in a micro ATX case is the best choice due to space limitation
 

yep i am not a fan of big case i always had Micro ATX and at same time i use it for rendering purpose mostly while still being capable of playing so i really never cared about SLI
i got myself a titan 6gb that is best for rendering iray or RT-vray and that's all i need
 
i just like small format pc
 
but definitely is better going water for the CPU in a m-atx while the gpu i left it @ air

Waiting (and watching the UPS tracker) for the delivery of the X99 back to Newegg, it looks like they'll have it Monday.  Then, another few days to process and *then* order up the mX99.  
 
I love waiting.. :)