It might help if you list your entire system specs and monitor  as well .....&  did you just do the 'upgrade' version of Win 10 ?, - or did you also later do the full wipe and install fresh copy of  10 ?
 
 

Sorry here it is

Intel 3770k
Intel dz77ga-70k
Evga gtx 980ti sc
Asus vg248qe 144hz

Upgraded to win 10 from 8.1 ... I didn't do a full wipe as I wanted to keep all my settings and files as is

rjohnson11
I have two GTX 980ti cards in SLI and they are happily running fine in Windows 10 pro.
 
Yes, definitely need your system specs to assist you further

+1. I have 980 Ti SC+ in SLI and they are running fine too. What is the version of nvidia drivers are you using ? The latest drivers are fine but flickering shadows and sudden FPS drops ( less than a second ) issues in Witcher 3 are still there from 355.80.
 
 
Didn't try Farcry 4 for the TDR crash.

Antoniop84@mhijazi...did you do a clean win 10 install or upgrade from 7/8?
 
Thanks

Acutally I had 780's in before I swapped them with 980 Ti's . But the installation before swapping cards was fresh Windows 10 isntallation. 

ok guys thanks for your help...I will try that tonight along with a few other things I stumbled across and update tomorrow.
 
Thanks

i got a corsair hx850i

EVGA_JacobF
What is the summary/error that it shows in Device manager?

+1

Try this...
 
#1 Download driver 355.82 to your desktop & download the latest version of DDU to your desktop.
 
#2 Unplug ethernet cable from motherboard to disconnect the internet.
 
#3 Uninstall the nvidia drivers normally.
 
#4 Use DDU (Display driver uninstaller) in safe mode to clean out all your nvidia drivers. Use the clean and restart (highly recommended) option.
 
#5 Delete video GUID's using regedit. Click the start button and type regedit and hit enter. For windows 8/10 hit the windows key + r and type in regedit and hit enter. Navigate to...
- HKEY_LOCAL_MACHINE\SYSTEM\ControlSet001\Control\Video (highlight the Video key and press the delete key.)
- HKEY_LOCAL_MACHINE\SYSTEM\ControlSet002\Control\Video (highlight the Video key and press the delete key.)
- HKEY_LOCAL_MACHINE\SYSTEM\CurrentControlSet\Control\Video (highlight the Video key and press the delete key.)
NOTE: When deleting the video key you will be prompted with an error saying "Error deleting key, Cannot delete Video: Error while deleting key." Just ignore the error and select OK, all keys within the Video key will be deleted except for ones that cannot be deleted.
 
#6 Reboot PC.
 
#7 Do step #5 again.
 
#8 Reboot PC.

#9 Perform a clean installation of video drivers.

1. Uninstall Precision X/Afterburner if installed, make sure to select "no" to saving profiles if asked.  Reboot the PC now if you had to uninstall PX or Afterburner.
2. Run the graphics installer located on your desktop. 
3. Select custom advanced install, under custom installation options uncheck all options except the physx system software, if you have a 3D capable monitor and would like to use 3D at some point please select both 3D options, check mark perform clean install, then click next to install the driver, reboot when asked.

#10 Connect ethernet cable.

Yes, highlight the video key and press the del key.

Antoniop84
Trying it now... Is it ok I don't have controlset002?

Yes.

No problem. Glad it worked for you. 

Onboard graphics should be disabled when using your dedicated gpu. To try and fix it you could try unplugging the ethernet cable from motherboard, opening device manger, right click the 4600 under display adapters & select uninstall, check mark "delete the driver software for this device" if shown, then select ok, close device manger and reboot pc, install latest driver.

No problem.